Abstract
THE most physiological substrate for fibrinolytic assays is non-heated fibrin. However, the clot formed from ordinary fraction-I, or even from highly purified fibrinogen, is generally heavily contaminated by plasminogen; this interferes with the protease content of the test solution.
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VIGNAL, A., BLATRIX, C. & STEINBUCH, M. Fibrinogen Free of Plasminogen as Substrate for Fibrinolytic Assays. Nature 193, 693 (1962). https://doi.org/10.1038/193693a0
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DOI: https://doi.org/10.1038/193693a0
