Abstract
SKIN has been removed from sheep fœtuses, stored until after the birth of the donor and then replaced as an autograft to a position where its subsequent development could be closely watched. The object of this was to by-pass any systemic factors peculiar to the latter half of gestation which might influence the development of the skin. Also, by having the developing skin on the surface of the post-natal animal, there are many opportunities for experimental work such as altering the rate of expansion and imposing various other conditions.
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References
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Billingham, R. E., and Medawar, P. B., J. Exp. Biol., 29, 454 (1952).
Barnard, C. N., Surgery, 41, 805 (1957).
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HICKMAN, J., RUDALL, K. & WICKHAM, G. Storage of Fœtal Sheep Skin and its Growth as an Autograft on the Lamb. Nature 194, 394–395 (1962). https://doi.org/10.1038/194394a0
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DOI: https://doi.org/10.1038/194394a0
