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Demonstration and Possible Significance of Uricase in Human Pathogenic Fungi

Abstract

URICASE has been demonstrated in several moulds, bacteria, and yeasts1–4 and in animal tissues5,6. The elimination of uric acid as the chief waste product of nitrogen metabolism from birds and the isolation of certain human pathogenic fungi from soils in poultry pens and yards7–9 have suggested the possibility that these fungi may be able to utilize uric acid as a source of nitrogen for growth.

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TAYLOR, J. Demonstration and Possible Significance of Uricase in Human Pathogenic Fungi. Nature 194, 403–404 (1962). https://doi.org/10.1038/194403a0

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