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Lipid Content in Hyperdiploid and Hypertetraploid Cells isolated from the Hyperdiploid Ehrlich Ascites Tumour

Nature volume 194, pages 589–590 (1962)Cite this article

Abstract

THE hyperdiploid Ehrlich ascites tumour, described by Hauschka et al.1, contains about 5 per cent hypertetraploid cells. A varying amount of non-tumour cells (leucocytes) always occurs. By counter-streaming centrifugation a fraction of hyperdiploid cells could be obtained free from hypertetraploid cells which were concentrated into another fraction2. Inoculated into another mouse this fraction developed into a tumour with a higher proportion of hypertetraploid cells than the original one. Repeated fractionation followed by inoculation of this fraction increased the mean number of chromosomes per cell to about twice the original one, the mean number of chromosomes being estimated as the amount of deoxyribonucleic acid phosphorus (DNAP) per cell.

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Authors and Affiliations

  1. Institute of Zoophysiology, University of Uppsala,

    PER ERIC LINDAHL

Authors
  1. PER ERIC LINDAHL
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LINDAHL, P. Lipid Content in Hyperdiploid and Hypertetraploid Cells isolated from the Hyperdiploid Ehrlich Ascites Tumour. Nature 194, 589–590 (1962). https://doi.org/10.1038/194589a0

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