Abstract
A STRAIN of mice suffering from hæmolytic anæmia of the autoimmune type has been established by one of us (M. B.). This strain designated NZB/Bl is now in the 52nd generation of brother–sister mating. Serological signs of the disease, such as agglutinating antibodies1 and positive Coombs's tests2, appear in a few animals from the 4th month of life onward, the incidence rising to virtually 100 per cent in animals older than 9 months.
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References
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BIELSCHOWSKY, M., BIELSCHOWSKY, F. Reaction of the Reticular Tissue of Mice with Autoimmune Hæmolytic Anæmia to 2-Aminofluorene. Nature 194, 692 (1962). https://doi.org/10.1038/194692a0
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DOI: https://doi.org/10.1038/194692a0
