Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Variations in Inorganic Pyrophosphatase and Glutaminase in the Liver and Brain of Mice poisoned by Carbon Tetrachloride

Abstract

J. HAGEN1 has shown that carbon tetrachloride poisoning in factory workers induces extensive biochemical and metabolic changes in the central nervous system, liver and kidneys. On investigating the action of carbon tetrachloride in mice, Frunder et al.2–5 found significant changes in the metabolism of carbohydrates, proteins and lipids in the liver parenchyma.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Hagen, J., Klinika professionalnih zabolevanii, Medghiz, Leningrad, 276 (1961).

    Google Scholar 

  2. Frunder, H., Fisher, W., and Börnig, H., Hoppe Seyl. Z. phys. Chem., 306, 112 (1956).

    Article  CAS  Google Scholar 

  3. Frunder, H., Börnig, H., Richter, G., and Stode, K., Hoppe Seyl. Z. phys. Chem., 307, 161 (1957).

    Article  CAS  Google Scholar 

  4. Börnig, H., Stode, K., Frunder, H., and Richter, G., Hoppe Seyl. Z. phys. Chem., 310, 232 (1958).

    Article  Google Scholar 

  5. Richter, G., Frunder, H., and Börnig, H., Hoppe Seyl. Z. phys. Chem., 310, 249 (1959).

    Article  Google Scholar 

  6. Schench, D., and Rapoport, S., Acta biol. Med. Germ., 7, 113 (1961).

    Google Scholar 

  7. Rafter, G. W., J. Biol. Chem., 230, 543 (1958).

    Google Scholar 

  8. Seal, U. S., and Binkley, F., J. Biol. Chem., 228, 193 (1957).

    CAS  PubMed  Google Scholar 

  9. Richterich von Boerle, E., Goldstein, L., and Dearborn, E., Enzymologia, 18, 190 (1957).

    Google Scholar 

  10. Goldstein, L., Richterich von Boerle, E., and Dearborn, E., Enzymologia, 18, 263 (1957).

    Google Scholar 

  11. Palladin, A. V., Voprosî biohimii nervnoi sistemî, Izd. Akadem. Nauk Ucranskoi S.S.R., Kiev, 148 (1957).

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

ABABEI, L., CǍPÂLNǍ, S. & STEFǍNESCU, P. Variations in Inorganic Pyrophosphatase and Glutaminase in the Liver and Brain of Mice poisoned by Carbon Tetrachloride. Nature 194, 983–984 (1962). https://doi.org/10.1038/194983b0

Download citation

  • Issue date:

  • DOI: https://doi.org/10.1038/194983b0

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing