Abstract
THE artificial mouth is a device for simulating in vitro the principal oral conditions presumably involved in dental caries1. Qualitatively, the in vitro lesions produced in human teeth are similar to those produced naturally2–4. The method has been used for the quantitative evaluation of anti-caries agents and dentifrices5–7.
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PIGMAN, W., BRASHER, J. & KOULOURIDES, T. Cariogenicity of Common Sugars as evaluated in the Artificial Mouth. Nature 195, 190–191 (1962). https://doi.org/10.1038/195190b0
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DOI: https://doi.org/10.1038/195190b0