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Action of Ionizing Radiation on Rat Liver Cell Nuclei
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  • Letter
  • Published: 25 August 1962

Action of Ionizing Radiation on Rat Liver Cell Nuclei

  • G. SCHOLES1,
  • J. J. WEISS1 &
  • C. M. WHEELER1 

Nature volume 195, page 802 (1962)Cite this article

  • 470 Accesses

  • 5 Citations

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Abstract

THE site of attack by OH radicals on the various components of some cell nuclei has been explored using the radiation-induced carboxylation technique recently described1. This involves irradiation of oxygen-free suspensions of the nuclei in the presence of sodium bicarbonate, under conditions where the radicals can react with the nuclear constituents. The negative polarons2, (H2O)− produced from the water react with the bicarbonate according to :

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References

  1. Scholes, G., Simic, M., and Weiss, J., Nature, 188, 1019 (1960).

    Article  ADS  CAS  Google Scholar 

  2. Hayon, E., and Weiss, J., Proc. Second Intern. Conf. Peaceful Uses of Atomic Energy, Geneva, 29, 80 (1958). Weiss, J., Nature, 186, 751 (1960).

    Google Scholar 

  3. Dounce, L., in The Nucleic Acids, edit. by Chargaff, E., and Davidson, J. N., 2, 93 (Academic Press, Inc., New York, 1955).

    Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Chemistry, King's College, University of Durham, Newcastle upon Tyne, 1

    G. SCHOLES, J. J. WEISS & C. M. WHEELER

Authors
  1. G. SCHOLES
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  2. J. J. WEISS
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  3. C. M. WHEELER
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SCHOLES, G., WEISS, J. & WHEELER, C. Action of Ionizing Radiation on Rat Liver Cell Nuclei. Nature 195, 802 (1962). https://doi.org/10.1038/195802a0

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  • Issue date: 25 August 1962

  • DOI: https://doi.org/10.1038/195802a0

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