Abstract
Wissmann and Nitschmann1, studying the action of rennin on α-casein by the method of Sanger2, found, after the action of rennin for 30 min., not only the original N-terminal amino-acids arginine and lysine but also a new N-terminal amino-acid, namely, phonylalanine. Thus these workers concluded that the non-protein nitrogen which is formed by the transformation: α-casein → para-α-casein + non-protein nitrogen, results from the rupture of a peptide bond.
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References
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DE KONING, P., STADHOUDERS, J. Appearance of New N-Terminal Groups by the Action of Rennin on Casein. Nature 195, 802–804 (1962). https://doi.org/10.1038/195802b0
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DOI: https://doi.org/10.1038/195802b0
