Abstract
REPORTS in the literature have indicated that the infusion of tris (hydroxy-methyl) amino methane (tris) results in increased blood pH and carbon dioxide content, with no change or a lowering of Pco2 (ref. 1). Pulmonary ventilation has been reported to decrease, while large amounts of ‘bicarbonate’ are excreted through the kidneys2. These results have been interpreted in part as showing a respiratory centre responsiveness to pH in the absence of a change in Pco2 (ref. 2).
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POPPELL, J., VANAMEE, P. An Alveolar-Arterial Pco2 Discrepancy. Nature 195, 809–810 (1962). https://doi.org/10.1038/195809a0
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DOI: https://doi.org/10.1038/195809a0
