Aminopterin as an Inducing Agent in Bacteriocinogenic Bacteria

Abstract

INDUCTION of lysogenic bacteria was first produced by the use of ultra-violet light¹. It was shown later that other radiations², nitrogen mustard, ethyleneimines, epoxides and organic peroxides³ can also induce lysogenic bacteria to produce phage. The process of induction is not yet clear. Several lines of evidence indicate that the primary lesion initiated by inducing agents could be an alteration in the nucleic acid economy of the host, an effect of unbalanced growth⁴.