Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Removal and Regeneration of the Cell Coating in Tumour Cells

Nature volume 196, page 170 (1962)Cite this article

Abstract

SOME ascitic tumour cells are coated with a mucopolysaccharide stainable by the Hale reaction1. Experiments were carried out to characterize more specifically the chemical nature of this cell coating and to study the dynamics of cell coat formation. Cells of ascitic mammary carcinoma TA3 were used in vitro. Experiments were carried out to determine whether some proteases and mucinases remove the cell coating, and, after removal, regeneration of the cell coating occurs.

Access through your institution
Buy or subscribe

This is a preview of subscription content, access via your institution

Access options

Access through your institution

Buy this article

  • Purchase on SpringerLink
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Gasic, G., and Baydak, T., Proc. Inter. Symp. Biological Interactions in Normal and Neoplastic Growth. Henry Ford Hospital, Detroit, May 1961 (Little, Brown and Co., Boston, in the press).

  2. Love, R., and Liles, R. H., J. Histochem. Cytochem., 7, 164 (1959).

    Article  CAS  Google Scholar 

  3. Mowry, R. W., Lab. Invest., 7, 566 (1958).

    CAS  Google Scholar 

  4. Weiss, L., Nature, 191, 1108 (1961).

    Article  ADS  CAS  Google Scholar 

  5. Gasic, G., Loebel, F., and Badinez, O., Nature, 185, 864 (1960).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pathology, School of Medicine, University of Pennsylvania, Philadelphia, 4

    G. GASIC & T. GASIC

  2. Department of Oncology, University of Chile,

    G. GASIC & T. GASIC

Authors
  1. G. GASIC
    View author publications

    Search author on:PubMed Google Scholar

  2. T. GASIC
    View author publications

    Search author on:PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

GASIC, G., GASIC, T. Removal and Regeneration of the Cell Coating in Tumour Cells. Nature 196, 170 (1962). https://doi.org/10.1038/196170a0

Download citation

  • Issue date:

  • DOI: https://doi.org/10.1038/196170a0

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing