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Heparin and Blood Lipids in Fasted Individuals

Abstract

IT is well known that intravenous administration of heparin induces in hyperlipæmic individuals a clearing of the plasma turbidity1. This effect has been explained by changes in physicochemical properties of the circulating lipids, consisting mainly of hydrolysis and dissolution of the fat in the plasma, due to the activation of a lipæmia-clearing mechanism2. There is also a suggestion that heparin could accelerate the removal of hydrolysed lipids from the blood stream since it was found that it induces a decrease in total fatty acids of plasma in hyperlipæmic rats3.

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GRANITSAS, A., ACHIMASTOS, A. Heparin and Blood Lipids in Fasted Individuals. Nature 196, 173–174 (1962). https://doi.org/10.1038/196173b0

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