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Leukæmia in the Progeny of Rats inoculated with a Leukæmogenic Virus

Nature volume 196, pages 283–284 (1962)Cite this article

Abstract

VERTICAL transmission of virogenic leukæmia, that is, the occurrence of leukæmia in the untreated progeny of animals inoculated with a leukæmogenic virus, has been observed with four different viruses of murine origin1–5. The phenomenon is not a uniform one. For example, Moloney's virus is transmitted in some strains of mice with little, if any, change of incidence through successive generations ; in other strains, equally susceptible to inoculated virus, it is not transmitted at all4,6. Gross's virus in one strain passes with undiminished incidence to the first generation, but incidence falls off rapidly in subsequent generations ; in other susceptible strains it is not transmitted7–9.

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References

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Authors and Affiliations

  1. Cancer Research Department, London Hospital Medical College, London, E.1

    M. H. SALAMAN & J. J. HARVEY

Authors
  1. M. H. SALAMAN
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  2. J. J. HARVEY
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SALAMAN, M., HARVEY, J. Leukæmia in the Progeny of Rats inoculated with a Leukæmogenic Virus. Nature 196, 283–284 (1962). https://doi.org/10.1038/196283a0

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