Abstract
THE lowering of glycogen store in normal animal tissues during the growth of a transplanted hepatoma and the absence of glycogen in neoplastic tissues are commonly observed phenomena. The complex processes which result in removal of glycogen from normal tissues during the growth of a transplanted tumour are not fully understood. However, evidence is available for low glycogen formation in tumours and is based mainly on the assumption of a defective system of glycogen synthesis1,2.
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NIGAM, V. Regulatory Mechanisms of Glycogen Deposition in Liver of Normal and Tumour-bearing Rat, and in Novikoff Ascites Hepatoma. Nature 196, 478–480 (1962). https://doi.org/10.1038/196478a0
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DOI: https://doi.org/10.1038/196478a0