Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Mitochondrial Changes during the Process of Awakening from Hibernation

Abstract

LIVER mitochondrial succinoxidase (SO) activity of hibernating hamsters is markedly lower than that of cold-acclimatized awake controls when assayed at the body temperature of the hibernating hamsters, 7° C1,2. However, when the same mitochondrial preparations are assayed at the body-temperature of awake hamsters, 37° C, no such difference is observed1,2. It is apparent that an SO-inhibiting substance or mechanism in the mitochondria of the hibernating animals operates at 7° C. but not at 37° C.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Chaffee, R. R. J., thesis, Harvard University (1957).

  2. Chaffee, R. R. J., Hoch, F. L., and Lyman, C. P., Amer. J. Physiol., 201, 29 (1961).

    CAS  PubMed  Google Scholar 

  3. Lyman, C. P., and Chatfield, P. O., Physiol. Rev., 35, 403 (1955).

    Article  CAS  Google Scholar 

  4. Hoch, F. L., and Lipmann, F., Proc. US. Nat. Acad. Sci., 40, 909 (1954).

    Article  ADS  CAS  Google Scholar 

  5. Lehninger, A. L., Rev. Mod. Phys., 31, 136 (1959).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

CHAFFEE, R. Mitochondrial Changes during the Process of Awakening from Hibernation. Nature 196, 789–790 (1962). https://doi.org/10.1038/196789a0

Download citation

  • Issue date:

  • DOI: https://doi.org/10.1038/196789a0

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing