Abstract
BASE ratios can be determined with microelectrophoresis (microphoresis) in as little as 5 × 10−10 g RNA1, a sensitivity which permits intracellular analysis in suitable material. It would be of interest for turn-over studies to evaluate radioactivity in the separated RNA components. Autoradiography is the simplest tool for this purpose, both because of its sensitivity and high resolution.
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References
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Edström, J.-E., Grampp, W., and Schor, N., J. Biophys. Biochem. Cytol., 11, 549 (1961).
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SIRLIN, J., EDSTRÖM, JE. A Combined Microphoresis-Autoradiography Technique. Nature 197, 89–90 (1963). https://doi.org/10.1038/197089a0
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DOI: https://doi.org/10.1038/197089a0
