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Isolation of Lampterol, an Antitumour Substance from Lampteromyces japonicus

Abstract

AN intensive screening of about 600 mushrooms for antitumour substances1 revealed that Lampteromyces japonicus, a bioluminescent mushroom which grows on rotten beech in October, possessed high activity. The mushroom is also known for its toxicity, which has occasionally caused fatal accidents due to its similarity in appearance to edible mushrooms. Isolation of the toxic principle in a semi-pure state was reported by Nakai in 1958 2.

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References

  1. Komatsu, N., Hamada, M., Nakazawa, S., Ogata, S., Yamamoto, A., Terakawa, H., and Yamamoto, T., J. Ferment. Assoc., 19, 464 (1961); Jap. J. Bact., 16, 746 (1961) (in Japanese).

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  2. Nakai, K., Medicine and Biology (in Japanese), 49, 129 (1958).

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  3. Yamazaki, S., Nitta, K., Nogi, M., Takeuchi, T., Yamamoto, T., and Umezawa, H., J. Antibiotics, A, 9, 135 (1956).

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NAKANISHI, K., TADA, M., YAMADA, Y. et al. Isolation of Lampterol, an Antitumour Substance from Lampteromyces japonicus. Nature 197, 292 (1963). https://doi.org/10.1038/197292a0

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