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Antihistaminic Action of Lysozyme

Nature volume 197, page 496 (1963)Cite this article

Abstract

IT was previously shown that heparin and mucin bind histamine1,2. For this reason we worked with an enzyme acting on mucopolysaccharides, and looked for some modifications of histamine action. Lysozyme inhibits the action of histamine on the isolated guinea pig's ileum. The threshold is about 10−9 (w/v). No inhibitor action was observed towards acetylcholine, serotonin and barium.

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References

  1. Parrot, J.-L., and Laborde, C., C.R. Soc. Biol., Paris, 145, 1047 (1951).

    CAS  Google Scholar 

  2. Parrot, J.-L., C.R. Soc. Biol., Paris, 142, 631 (1948); J. Physiol., Paris, 41, 251 A (1949).

    CAS  Google Scholar 

  3. Konzett, H., and Rössler, R., Arch. exp. Pathol. Pharmakol., 195, 71 (1940).

    Article  Google Scholar 

  4. Further details will appear in J. Physiol., Paris, 54 (in the press).

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Authors and Affiliations

  1. Laboratoire de Physiologie pathologique, Hôpital Boucicaut, Paris

    JEAN-LOUIS PARROT & GEORGES NICOT

Authors
  1. JEAN-LOUIS PARROT
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  2. GEORGES NICOT
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PARROT, JL., NICOT, G. Antihistaminic Action of Lysozyme. Nature 197, 496 (1963). https://doi.org/10.1038/197496a0

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