Utilization of Cell Chromosome Number for diagnosing Cancer Cells in Effusion

Abstract

THE karyological study of cancer cells has recently been a field of increased interest. While noting that most human cancer cells have abnormal idiograms, the various contributions have been concerned largely with the theoretical nature of cancer and have provided only a minimal amount of clinically useful information^1–5. Jacob⁶ has suggested that malignancy may be diagnosed by chromosome counts. It therefore appears worthwhile to emphasize that determining the approximate number of chromosomes of cells frequently will provide accurate diagnoses of cancer.