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Glycoprotein Excretion following the Injection of Papain into Rabbits

Nature volume 197, page 707 (1963)Cite this article

Abstract

UNACTIVATED papain, injected intravenously into rabbits, passes from the blood to cartilage tissues where it is activated locally, causing ear collapse due to depolymerization of chondromucoprotein (chondroitin sulphate–protein complexes). The enzymatic products (for which the term ‘chondromucopeptides’ is proposed) leach out of the cartilage into the blood and are excreted in the urine1.

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Authors and Affiliations

  1. Department of Pathology, Institute of Orthopædics, Royal National Orthopædic Hospital, Stanmore, Middlesex

    A. J. ANDERSON, C. H. LACK & S. Y. ALI

Authors
  1. A. J. ANDERSON
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  2. C. H. LACK
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  3. S. Y. ALI
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ANDERSON, A., LACK, C. & ALI, S. Glycoprotein Excretion following the Injection of Papain into Rabbits. Nature 197, 707 (1963). https://doi.org/10.1038/197707a0

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