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Ineffectiveness of Autotransplantation on Growth of the Methylcholanthrene Sarcoma in Rats and Mice

Abstract

RECENTLY, Ishibashi et al.1 reported that the subcutaneous autotransplantation of a patient's own tumour slices was effective against the growth of the original tumour and sometimes caused its regression. It seems, however, that experimental evidence on the effectiveness of autotransplantation is not sufficient to try it against human cancer. Attempts were made in this laboratory to examine whether autograft of tumour induced by methylcholanthrene could increase the survival days of the host after appearance of a tumour.

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References

  1. Ishibashi, Y., Hattori, T., Fujii, G., Okada, K., Sekiguchi, M., Ashikawa, K., and Motoya, K., Jap. J. Exp. Med., 31, 1 (1961).

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  2. Kondo, K., Nozawa, K., Tomita, T., and Ezaki, K., Jikkendobutsu, 6, 107 (1957).

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  3. Rhodes, E. L., Nature, 193, 1091 (1962).

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MATSUYAMA, M., SUZUMORI, K., MAEKAWA, A. et al. Ineffectiveness of Autotransplantation on Growth of the Methylcholanthrene Sarcoma in Rats and Mice. Nature 197, 805 (1963). https://doi.org/10.1038/197805a0

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