Abstract
Two main hæmoglobin-binding serum globulin fractions have been demonstrated by using the technique of immuno-electrophoresis. One precipitation line corresponds to the α2 region and is sometimes doubled1; the other to the β region1,2. On the other hand, starch-gel electrophoresis shows numerous hæmoglobin-binding globulins which are now well known as the haptoglobins 1 and 2 of Smithies3. The relation between the immuno-electrophoretic and starch-gel haptoglobins is not yet quite clear. Allison's4 hypothesis of polymerization of the α2 haptoglobins is yet to be confirmed.
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References
Tombs, M. P., Nature, 186, 1055 (1960).
Korinek, J., Paluska, E., and Mach, O., Clin. Chim. Acta, 6, 388 (1961).
Smithies, O., and Poulik, M. D., Nature, 177, 1033 (1956).
Allison, A. C., Nature, 183, 1312 (1959).
Afonso, E., Clin. Chim. Acta, 7, 545 (1962).
Swarup, S., Gosh, S. K., and Chatterjea, J. B., Bull. Calcutta School Trop. Med., 7, 150 (1959).
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AFONSO, E., PROENÇA, J. Hæmoglobin-binding Serum Globulins. Nature 198, 1100–1101 (1963). https://doi.org/10.1038/1981100a0
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DOI: https://doi.org/10.1038/1981100a0
