Abstract
SULPHATE assimilation in Aspergillus nidulans has been shown to involve a step in which thiosulphate reacts with a 3-carbon compound, probably serine, to form S-sulphocysteine as the immediate precursor of cysteine1–5. However, the enzymatic mechanism involved in this assimilatory step has not yet been elucidated. This communication shows that an enzyme preparation obtained from A. nidulans catalyses the condensation of thiosulphate with serine to form S-sulphocysteine if adenosine triphosphate (ATP) and pyridoxal phosphate are added as cofactors.
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NAKAMURA, T., SATO, R. Enzymatic Synthesis of S-Sulphocysteine from Thiosulphate and Serine. Nature 198, 1198 (1963). https://doi.org/10.1038/1981198a0
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DOI: https://doi.org/10.1038/1981198a0
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