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Microbial Transformation of n-Octane into Dicarboxylic Acids

Abstract

IN 1960 Kester and Foster1 demonstrated the conversion of certain liquid hydrocarbons to the corresponding alkanedioic acids in cultures of a Gram-positive bacterium. n-Alkanes possessing between 10 and 14 carbon atoms were shown to undergo this process of di-terminal oxidation. Evidence has been obtained2,3 that n-decanoic and 10-hydroxydecanoic acids are intermediates in the oxidation of n-decane to n-decanedioic acid.

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References

  1. Kester, A. S., and Foster, J. W., Bact. Proc., 168 (1960).

  2. Kester, A. S., Dissertation Abstr., 22, 3350 (1962).

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  3. Foster, J. W., in The Oxygenases, edit. by Hayaishi, O. (Academic Press, New York) (in the press).

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ALI KHAN, M., HALL, A. & ROBINSON, D. Microbial Transformation of n-Octane into Dicarboxylic Acids. Nature 198, 289 (1963). https://doi.org/10.1038/198289a0

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