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Release of Calcium in the Myoneural Junction

Abstract

THERE is a good evidence that calcium might be the link between bioelectrical events in the muscle cell membrane and myofibrillar contraction1. On the other hand, it is generally accepted that most of the intracellular calcium is present in a strongly bound form2. Accordingly, histochemical methods are not capable of demonstrating calcium in muscle fibres, except by means of micro-incineration techniques3. Recent experiments, performed by several authors1,2, suggest that muscular activity results in liberation of bound calcium. The objective of our investigations was to demonstrate histochemically this release of calcium.

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References

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CSILLIK, B., SÁVAY, G. Release of Calcium in the Myoneural Junction. Nature 198, 399–400 (1963). https://doi.org/10.1038/198399a0

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