Abstract
WE have previously reported the effects of various steroids on the macrophage activity of the reticulo-endothelial system1,2, and have shown that in general the œstrogens gave rise to stimulation3 while cortisone and related substances caused depression4. It is therefore pertinent that such compounds as 3β-methoxyandrost-5-en-16β-ol5,6 having a strong cytostatic activity should be investigated with regard to their effect on reticulo-endothelial phagocytosis.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Nicol, T., and Bilbey, D. L. J., Reticuloendothelial Structure and Function (Ronald Press Co., New York, 1960).
Bilbey, D. L. J., and Nicol, T., Nature, 182, 647 (1958).
Nicol, T., Bilbey, D. L. J., and Ware, C. C., Nature, 181, 1538 (1958).
Nicol, T., and Bilbey, D. L. J., Nature, 182, 606 (1958).
Huffman, M. N., Lott, M. H., and Tillotson, A., J. Biol. Chem., 222, 447 (1956).
Jones, R. W., Rebell, G., and Huffman, M. N., Nature, 181, 48 (1958).
Nicol, T., Bilbey, D. L. J., and Druce, C. G., Nature, 190, 418 (1961).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
NICOL, T., BILBEY, D. Effect of Certain Cytostatic and Fungistatic Steroids on Activity of the Reticulo-endothelial System. Nature 198, 492 (1963). https://doi.org/10.1038/198492a0
Issue date:
DOI: https://doi.org/10.1038/198492a0
