Abstract
ALTHOUGH many extensive investigations in animals1–3 have demonstrated the existence of renal medullary hyperosmolality suggestive of a counter-current mechanism of urine concentration, direct evidence of medullary hyperosmolality in man has never been obtained hitherto. We have examined the tissue concentrations of sodium, potassium, urea and ammonia in human kidneys removed at operation or shortly after death, using standard techniques4.
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BERLYNE, G., HOERNI, M. Urine-concentrating Mechanism in Man. Nature 199, 78 (1963). https://doi.org/10.1038/199078a0
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DOI: https://doi.org/10.1038/199078a0
