Hydrolysis of Some Antibiotics and of their Decomposition Products in the Presence of Cation Exchange Resins

Abstract

THE conditions under which some antibiotics are hydrolysed may be important for the isolation and identification of the products of their decomposition since these are used in investigations of the structure of the antibiotics. During hydrolysis with mineral acids some moieties, such as carbohydrates, may be destroyed, and much humin may be produced which makes it difficult to isolate the more stable products of decomposition in pure form.