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Metabolism of 3-Hydroxyanthranilic Acid labelled with Carbon-14 Carboxyl in Normal and Neoplastic Mice

Abstract

THE o-aminophenol, 3-hydroxyanthranilic acid (3-OHAA) is a metabolite of tryptophan normally present in urine in trace quantities. Recent observations have been concerned both with the carcinogenic property of 3-OHAA to induce cancer of the bladder and with elevated levels of urinary excretion of 3-OHAA in neoplastic diseases1.

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HANKES, L., SCHMAELER, M. & STONER, R. Metabolism of 3-Hydroxyanthranilic Acid labelled with Carbon-14 Carboxyl in Normal and Neoplastic Mice. Nature 200, 676–677 (1963). https://doi.org/10.1038/200676b0

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  • DOI: https://doi.org/10.1038/200676b0

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