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The Cla(Caldwell) Antigen : a New and Rare Human Blood Group Antigen related to the MNSs System

Abstract

Two unrelated families have been found to demonstrate the inheritance of a new and rare red cell antigen, the specificity of which appears to differ from that of all other antigens so far described. It is proposed that the new antigen be named Cla(Caldwell). The close genetical linkage of Cla to the MNSs system has been established. In the two families here reported the coupling of Cla is with Ms throughout.

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References

  1. Cameron, C., Graham, F., Dunsford, I., Sickles, G., Macpherson, C. R., Cahan, A., Sanger, R., and Race, R. R., Brit. Med. J., ii, 29 (1959).

  2. Race, R. R., and Sanger, R., Blood Groups in Man, fourth ed., 94 (Blackwell Sci. Pub., Oxford, 1962).

    Google Scholar 

  3. Wallace, J., Milne, G. R., Mohn, J. F., Lambert, R. M., Rosamilia, H. G., Moores, P., Sanger, R., and Race, R. R., Nature, 179, 478 (1957).

    Article  ADS  CAS  Google Scholar 

  4. Cleghorn, T. E., M.D. thesis, Sheffield (1961).

  5. Cleghorn, T. E., Nature, 195, 297 (1962).

    Article  ADS  CAS  Google Scholar 

  6. Hart, Mia v.d., Veer, Marga v.d., Loghem, J. J. van, Sanger, R., and Race, R. R., Vox Sang., 3, 261 (1958).

    Article  Google Scholar 

  7. Swanson, J., and Matson, G. A., Vox Sang., 7, 585 (1962).

    CAS  PubMed  Google Scholar 

  8. Allan, jun., F. H., Corcoran, P. A., Kenton, H. B., and Breare, N., Vox Sang., 3, 81 (1958).

    Google Scholar 

  9. Cleghorn, T. E. (in preparation).

  10. Anderson, C., Hunter, J., Zipursky, A., Lewis, M., and Chown, B., Transfusion, 3, 30 (1963).

    Article  CAS  Google Scholar 

  11. Rosenfield, R. E., and Graven, S. N. (unpublished observations).

  12. Wallace, J., and Milne, G. R., Proc. Seventh Cong. Intern. Soc. Blood Transfusion, 587 (1959).

  13. Simmons, R. T., and Albrey, J. A., Med. J. Austral., i, 8 (1963).

  14. Cleghorn, T. E., and Cahan, A. (in preparation).

  15. Sacks, M. S., and Jahn, E. F. (in preparation).

  16. Sutherland, J. M., and Haesler, W. E. E. (in preparation).

  17. Alter, A. A., Proc. Ninth Cong. Intern. Soc, Blood Transfusion (in the press).

  18. Levine, P., Celano, M. J., Wallace, J., and Sanger, R., Nature, 198, 596 (1963).

    Article  ADS  CAS  Google Scholar 

  19. Morton, J. A., Brit. J. Hæmat., 8, 134 (1962).

    Article  CAS  Google Scholar 

Download references

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WALLACE, J., IZATT, M. The Cla(Caldwell) Antigen : a New and Rare Human Blood Group Antigen related to the MNSs System. Nature 200, 689–690 (1963). https://doi.org/10.1038/200689a0

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