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Activity of Homologous and Heterologous Antisera prepared against the Same Antigen

Abstract

THE type of antibody activity present in antisera from different species directed towards the same antigen has important implications for the selection of the most effective antibody-producing animal for any given antigen-antibody system. In preparing antisera against mouse histocompatibility antigens, the use of mice of different histocompatibility types as antibody producers has proved very effective in differentiating these antigens1.

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LEVI, E., SCHECHTMAN, A. Activity of Homologous and Heterologous Antisera prepared against the Same Antigen. Nature 201, 1236–1237 (1964). https://doi.org/10.1038/2011236b0

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