Abstract
AMINOACETONITRILE partially protects the liver of the rat from necrosis observed in this organ 24 h after administration of dimethylnitrosamine1. In the experiments recorded here the effect of aminoacetonitrile was examined on one of the early lesions produced by dimethylnitrosamine in the rat liver, which consists of the inhibition of the protein synthesis2. This lesion is already detectable 3 h after administration of dimethylnitrosamine when the morphological lesions, observable under the light microscope, are missing or are scarcely noticeable2.
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References
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FIUME, L. Aminoacetonitrile Action on the Inhibition of the Protein Synthesis produced in the Rat Liver by Dimethylnitrosamine. Nature 201, 615 (1964). https://doi.org/10.1038/201615a0
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DOI: https://doi.org/10.1038/201615a0
