Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Prevention of Tumour Induction in SV40-infected Hamsters

Nature volume 202, pages 1126–1128 (1964)Cite this article

Abstract

SEVERAL investigators have attempted to prevent induction of tumours in animals infected by oncogenic viruses using immunization procedures during the latent period, that is, before the appearance of visible (palpable) tumours. In these experiments, virus-infected animals were inoculated during the latent period by live or killed tumour cells or by their components. Zilber and Baidakova1 indicated that the Bittner mammary tumour development in immunized mice could not be prevented although the duration of the latent period was longer. Goldner et al.2 failed to immunize SV40-infected hamsters by ‘Björklund-type’ tumour antigen; some stimulation effect on the tumour growth in such animals was obtained.

Access through your institution
Buy or subscribe

This is a preview of subscription content, access via your institution

Access options

Access through your institution

Buy this article

  • Purchase on SpringerLink
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Zilber, L. A., and Baidakova, Z. L., Voprosi oncologii, 1, 14 (1955) (in Russian).

    CAS  Google Scholar 

  2. Goldner, H., Girardi, A. Y., and Hilleman, M. R., Proc. Soc. Exp. Biol. Med., 114, 2, 456 (1963).

    Article  Google Scholar 

  3. Habel, K., Proc. Soc. Exp. Biol. Med., 106, 4, 722 (1961).

    Article  Google Scholar 

  4. Sjögren, O., Hellström, I., and Klein, G., Cancer Res., 21, 3, 329 (1961).

    Google Scholar 

  5. Defendi, V., Proc. Soc. Exp. Biol. Med., 113, 1, 12 (1963).

    Article  Google Scholar 

  6. Habel, K., and Eddy, B. E., Proc. Soc. Exp. Biol. Med., 113, 1 (1963).

    Article  CAS  Google Scholar 

  7. Koch, M. A., and Sabin, A. B., Proc. Soc. Exp. Biol. Med., 113, 1, 4 (1963).

    Article  Google Scholar 

  8. Klein, G., Sjögren, H. O., and Klein, E., Cancer Res., 22, 955 (1962).

    CAS  Google Scholar 

  9. Sachs, L., J. Nat. Cancer Inst., 29, 759 (1962).

    CAS  Google Scholar 

  10. Prigogina, E. L., and Stavrovskaya, A. A., Nature, 201, 934 (1964).

    Article  ADS  CAS  Google Scholar 

  11. Evans, C. A., Gorman, L. R., Ito, Y., and Weiser, R. S., J. Nat. Cancer Inst., 29, 277 (1962).

    CAS  PubMed  Google Scholar 

  12. Deichman, G. I., in Symp. Mechanisms of Cancerogenesis, Moscow (January 1964) (in Russian).

    Google Scholar 

  13. Deichman, G. I., and Kluchareva, T. E., Virology (in the press).

Download references

Author information

Authors and Affiliations

  1. Institute of Experimental and Clinical Oncology, Academy of Medical Sciences, Moscow, U.S.S.R.

    G. I. DEICHMAN & T. E. KLUCHAREVA

Authors
  1. G. I. DEICHMAN
    View author publications

    Search author on:PubMed Google Scholar

  2. T. E. KLUCHAREVA
    View author publications

    Search author on:PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

DEICHMAN, G., KLUCHAREVA, T. Prevention of Tumour Induction in SV40-infected Hamsters. Nature 202, 1126–1128 (1964). https://doi.org/10.1038/2021126b0

Download citation

  • Issue date:

  • DOI: https://doi.org/10.1038/2021126b0

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing