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Inhibition of Lipase Activity of Lung and Adipose Tissue by Phenothiazine Derivatives

Nature volume 202, pages 1336–1337 (1964)Cite this article

Abstract

AN increase in lipolysing activity of the blood has been recorded in some patients after injury of adipose tissue1,2. This increase is found to begin about three days after wounding. In the course of an investigation of the source of this lipase, we examined lung as well as adipose tissue, since lung is involved not only in the early complications of ‘fat embolism’, but also in ‘systemic fat embolism’, the signs of which appear after three days.

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Author information

Author notes

  1. W. C. HÜLSMANN

    Present address: Jonar Daniel Meijerplein, 3, Amsterdam-C

Authors and Affiliations

  1. Laboratory of Physiological Chemistry, University of Amsterdam,

    W. C. HÜLSMANN

  2. Mental Hospital, “St. Willibrordus Stichting”, Heiloo

    A. J. M. FABIUS

  3. Department of Physiology, University of Amsterdam,

    H. DE RUITER

Authors
  1. W. C. HÜLSMANN
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  2. A. J. M. FABIUS
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  3. H. DE RUITER
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HÜLSMANN, W., FABIUS, A. & DE RUITER, H. Inhibition of Lipase Activity of Lung and Adipose Tissue by Phenothiazine Derivatives. Nature 202, 1336–1337 (1964). https://doi.org/10.1038/2021336a0

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