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Measurement of Regional Blood Flow through the Skin from the Clearance of Krypton-85

Abstract

THIS communication presents a technique for the measurement of the blood flow through the skin which has been adapted from a method devised recently by Lassen and Ingvar1,2 for the measurement of local blood flow through the cerebral cortex. Krypton-85 dissolved in saline was injected into the carotid artery. Following the injection, blood flow was calculated from the rate of clearance of the isotope from the exposed cortex.

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References

  1. Lassen, N. A., and Ingvar, D. H., Experientia, 17, 42 (1961).

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  2. Ingvar, D. H., and Lassen, N. A., Acta Physiol. Scand., 54, 325 (1962).

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  3. Siggaard Andersen, O., Engel, K., Jörgensen, K., and Astrup, P., Scand. J. Clin. Lab. Invest., 12, 172 (1960).

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  4. Webb, Alfreda johnson, and Calhoun, M. Lois, Amer. J. Vet. Res., 15, 274 (1954).

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BELL, G., HARPER, A. Measurement of Regional Blood Flow through the Skin from the Clearance of Krypton-85. Nature 202, 704–705 (1964). https://doi.org/10.1038/202704a0

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