Unusual Urinary Compound in Patients Homozygous for Hereditary Atypical Serum Cholinesterase

Abstract

URINE from patients homozygous for hereditary atypical serum cholinesterase (HASC) and from normals (mainly laboratory personnel) was collected and refrigerated immediately. The cholinesterase genotype, as shown in Table 1, was determined by reported methods^1,2 on blood specimens drawn at the same time. The urine was lyophilized and reconstituted with distilled water to one-fifth the original volume. The concentrates were extracted by a slight modification of the method of Biran and Bartley³, as shown in Fig. 1.