Abstract
IN work which will be reported elsewhere it was found that certain extracts of the solanaceous plant Cestrum parqui caused a pronounced and prolonged elevation of the blood pressure of the anæsthetized rat. Since this reaction did not occur in the pithed animal, attempts were made to block the pressor effect at the autonomic ganglia. When hexamethonium failed to block the effects of C. parqui extracts it was decided to examine the effects of ganglion blocking agents per se in the rat.
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References
Kärki, N. T., Acta physiol. scand., 39, Supp. 132, 28 (1957).
Sultan Mawji, and Lockett, M. F., J. Pharm. Pharmacol., 15, 45 (1963).
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WHYTE, J. Anomalous Reactions of the Rat to Ganglion Blocking Agents. Nature 203, 307 (1964). https://doi.org/10.1038/203307a0
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DOI: https://doi.org/10.1038/203307a0
