Abstract
THE inclusion of 1 mg of fluoride per g of paste in a stannous fluoride dentifrice has led to the suggestion that chronic fluoride poisoning could arise during the prolonged use of such a preparation. Although it can be calculated that systemic fluorosis will not follow even the most abnormal use of a stannous fluoride paste this conclusion is, as yet, supported by only scanty experimental evidence.
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DUCKWORTH, R. Distribution and Excretion of Dentifrice Fluoride. Nature 204, 489–490 (1964). https://doi.org/10.1038/204489a0
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DOI: https://doi.org/10.1038/204489a0