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Influence of Amino-oxidase Inhibitors on the Psychomotor Depression produced by an Intraperitoneal Injection of Adrenaline in Mice
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  • Published: 01 March 1965

Influence of Amino-oxidase Inhibitors on the Psychomotor Depression produced by an Intraperitoneal Injection of Adrenaline in Mice

  • E. FISCHER1,2,
  • J. ORLANDO1,2 &
  • R. L. LUDMER1,2 

Nature volume 205, page 1225 (1965)Cite this article

  • 262 Accesses

  • 1 Citations

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Abstract

IN earlier papers1,2 the psychomotor depression produced by an intraperitoneal injection of catecholamines in mice was described. We found that the depression produced by adrenaline did not depend on peripheral autonomic phenomena and was not influenced by the adrenergic blocking agent phentolamine (‘Regitin’1); it was, however, inhibited by methylamphetamine2.

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References

  1. Fischer, E., and Amalfará, M. López, Nature, 193, 590 (1962).

    Article  ADS  CAS  Google Scholar 

  2. Fischer, E., Ludmer, R. L., and Kruglikoff, S. R., Nature, 204, 695 (1964).

    Article  ADS  CAS  Google Scholar 

  3. Melander, B., and Gliniecke, G., Acta Pharmacol. Tox., 18, 239 (1961).

    Article  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Laboratorio de Psicofarmacologia y Neuropsiquiatria Experimental, Hospital Nacional Neuropsiquiatrico (H), Vieytes 375, Buenos Aires

    E. FISCHER, J. ORLANDO & R. L. LUDMER

  2. Cátedra de Farmacología, Facultad de Ciencias Médicas, Universidad Nacional de Buenos Aires,

    E. FISCHER, J. ORLANDO & R. L. LUDMER

Authors
  1. E. FISCHER
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  2. J. ORLANDO
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  3. R. L. LUDMER
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FISCHER, E., ORLANDO, J. & LUDMER, R. Influence of Amino-oxidase Inhibitors on the Psychomotor Depression produced by an Intraperitoneal Injection of Adrenaline in Mice. Nature 205, 1225 (1965). https://doi.org/10.1038/2051225a0

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  • Published: 01 March 1965

  • Issue date: 20 March 1965

  • DOI: https://doi.org/10.1038/2051225a0

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