A Model of Tumour Growth in Irradiated Hosts

Abstract

IT has been found that local irradiation of the transplantation site prior to grafting experimental animal tumours influences the subsequent growth rate of the tumours and the survival time of the tumour-bearing hosts^1,2. While the results of the experiments indicated that irradiation of the host tissue slowed the growth of the tumours, more precise interpretation of the data seemed desirable. The following simple model was thus developed. In the light of this model, experimental data can be interpreted in a more meaningful fashion. In, addition, the approach utilized in the model may be useful in other problems of host-tumour interaction.