Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Postulated Chemical Basis for Observed Differences in the Enzymatic Behaviour of Chymotrypsin and Tryspin

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Hartley, B. S., Ann. Rev. Biochem., 29, 45 (1960).

    Article  CAS  Google Scholar 

  2. Compare with Balls, A. K., and Jansen, E. F., in Advances in Enzymology, 13, edit. by Nord, F. F., 321 (Interscience Publishers, Inc., New York, 1952).

    Google Scholar 

  3. Erlanger, B. F., and Cohen, W., J. Amer. Chem. Soc., 85, 358 (1963); Erlanger, B. F., Castleman, H., and Cooper, A. G., ibid., 85, 1872 (1963).

    Google Scholar 

  4. Inagami, T., and Sturtevant, J. M., J. Biol. Chem., 235, 1019 (1960).

    CAS  PubMed  Google Scholar 

  5. Bender, M. L., and Kaiser, E. T., J. Amer. Chem. Soc., 84, 2556 (1962).

    Article  CAS  Google Scholar 

  6. Schoellman, G., and Shaw, E., Biochem., 2, 252 (1963). Walsh, K. A., Kauffman, D. L., Sampath Kumar, K. S. V., and Neurath, H., Proc. U.S. Nat. Acad. Sci., 51, 301 (1964).

    Article  Google Scholar 

  7. Cohen, W., and Erlanger, B. F., J. Amer. Chem. Soc., 82, 3928 (1960). Cohen, W., Lache, M., and Erlanger, B. F., Biochem., 1, 686 (1962).

    Article  CAS  Google Scholar 

  8. Cunningham, L. W., J. Biol. Chem., 207, 443 (1954).

    CAS  PubMed  Google Scholar 

  9. Berends, F., Posthumus, C. H., Sluys, I. V. D., and Deierkauf, F. A., Biochim. Biophys. Acta, 34, 576 (1959).

    Article  CAS  Google Scholar 

  10. Jandorf, B. J., J. Amer. Chem. Soc., 78, 3686 (1956).

    Article  CAS  Google Scholar 

  11. Trowbridge, C. G., Krehbiel, A., and Laskowski, jun., M., Biochem., 2, 843 (1963).

    Article  CAS  Google Scholar 

  12. Inagami, T., and Murachi, T., J. Biol. Chem., 238, PC 1905 (1963).

    CAS  PubMed  Google Scholar 

  13. Erlanger, B. F., and Castleman, H., Biochim. Biophys. Acta, 85, 507 (1964).

    CAS  PubMed  Google Scholar 

  14. Hartley, B. S., Nature, 201, 1284 (1964).

    Article  ADS  CAS  Google Scholar 

  15. Kupcham, Morris S., Eriksen, S. P., and Friedman, M., J. Amer. Chem. Soc., 84, 4159 (1962).

    Article  Google Scholar 

  16. Bender, M. L., and Kaiser, E. T., J. Amer. Chem. Soc., 84, 2556 (1962).

    Article  CAS  Google Scholar 

  17. Bender, M. L., Schonbaum, G. R., and Zerner, B., J. Amer. Chem. Soc., 84, 2562 (1962).

    Article  Google Scholar 

  18. Bender, M. L., Clement, G. E., Kezdy, F. J., and Heck, H. d'A., J. Amer. Chem. Soc., 86, 3680 (1964).

    Article  CAS  Google Scholar 

  19. Jansen, E. F., Curl, A. L., and Balls, A. K., J. Biol. Chem., 189, 671 (1951).

    CAS  PubMed  Google Scholar 

  20. Cohen, W., and Erlanger, B. F., Biochim. Biophys. Acta, 52, 604 (1961).

    Article  CAS  Google Scholar 

  21. Labouesse, B., Oppenheimer, H. L., and Hess, G. P., Biochem. Biophys. Res. Commun., 14, 318 (1964).

    Article  CAS  Google Scholar 

  22. Erlanger, B. F., Kokowsky, N., and Cohen, W., Arch. Biochem. Biophys., 95, 271 (1961).

    Article  CAS  Google Scholar 

  23. Wilson, I. B., and Erlanger, B. F., J. Amer. Chem. Soc., 82, 6422 (1960).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

ERLANGER, B., COHEN, W., VRATSANOS, S. et al. Postulated Chemical Basis for Observed Differences in the Enzymatic Behaviour of Chymotrypsin and Tryspin. Nature 205, 868–871 (1965). https://doi.org/10.1038/205868a0

Download citation

  • Issue date:

  • DOI: https://doi.org/10.1038/205868a0

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing