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Oscillographic Polarography as a Method for Continuous Measurements of Inactivation of Penicillins by Penicillinase

Abstract

THE penicillins are enzymatically inactivated by penicillinase, which splits the β-lactam configuration producing penicilloic acids1. This process has so far been followed indirectly by manometric2, alkalimetric3, polarimetric4, iodometric5 and lengthy microbiological methods6,7.

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DUŠINSKÝ, G., ANTOLÍK, P. Oscillographic Polarography as a Method for Continuous Measurements of Inactivation of Penicillins by Penicillinase. Nature 206, 196–197 (1965). https://doi.org/10.1038/206196a0

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