Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Thymidine Diphosphate Nucleotides as Substrates in the Sucrose Synthetase Reaction

Abstract

THE UDP-glucose : D-fructose 2-glucosyltransferase (sucrose synthetase) is considered to be responsible for much of the synthesis of sucrose in plants1. Recently the important role of this enzyme in the degradation of sucrose in plant storage tissues was pointed out2. Other nucleotides, notably ADP, can also serve as glucosyl acceptors in this system3,4. Furthermore, tracer experiments with carbon-14 have shown that ADP-glucose formation from sucrose and ADP is a channel for the transfer of glucose from sucrose to starch4,5, and that TDP-glucose is a substrate for sucrose synthesis in a crude enzyme preparation obtained from wheat endosperm3.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Cardini, C. E., Leloir, L. F., and Chiriboga, J., J. Biol. Chem., 214, 149 (1955).

    CAS  PubMed  Google Scholar 

  2. Avigad, G., J. Biol. Chem., 239, 3613 (1964).

    CAS  PubMed  Google Scholar 

  3. Cardini, C. E., and Recondo, E., Plant and Cell Physiol., 3, 313 (1962).

    CAS  Google Scholar 

  4. De Fekete, M. A. R., and Cardini, C. E., Arch. Biochem. Biophys., 104, 173 (1964).

    Article  Google Scholar 

  5. Murata, T., Sugiyama, T., and Akazawa, T., Arch. Biochem. Biophys., 107, 92 (1964).

    Article  CAS  Google Scholar 

  6. Milner, Y., and Avigad, G., Israel J. Chem., 2, 316 (1964).

    Google Scholar 

  7. Paladini, A. C., and Leloir, L. F., Biochem. J., 51, 426 (1952).

    Article  CAS  Google Scholar 

  8. Kalina, M., and Avigad, G., Biochim. Biophys. Acta, 73, 652 (1963).

    Article  CAS  Google Scholar 

  9. Neufeld, E. F., and Hassid, W. Z., Adv. Carbohydrate Chem., 18, 309 (1963).

    CAS  Google Scholar 

  10. Ginsburg, V., Adv. Enzymol., 26, 35 (1964).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

MILNER, Y., AVIGAD, G. Thymidine Diphosphate Nucleotides as Substrates in the Sucrose Synthetase Reaction. Nature 206, 825 (1965). https://doi.org/10.1038/206825a0

Download citation

  • Issue date:

  • DOI: https://doi.org/10.1038/206825a0

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing