Effect of Anaesthetics on Mature Infections of Schistosoma mansoni in the White Mouse

Abstract

DURING experiments in which white mice infected for 8 weeks with Schistosoma mansoni were receiving antimonials intra-rectally and concurrent anaesthesia with ‘Nembutal’ (sodium pentobarbitone), it was noted that flukes removed from their normal sites in the mesenteric vessels to the intra-hepatic vessels. A hepatic shift also occurred in the anaesthetized control mice.