Abstract
As reviewed by Fruton1, cathepsins are intracellular proteinases with acid pH optima, ubiquitously found in animal tissues. In the mammal, highest concentrations of cathepsins are found in liver, kidney and spleen2–4. However, perfused rat liver was found to catabolize only 13–15 per cent of the total albumin broken down in the whole animal5.
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References
Fruton, J. S., in The Enzymes, 4, 223 (Academic Press, New York, 1960).
Tappel, A. L., Sawant, P., and Shibko, S., in Ciba Foundation Symposium on Lysosomes, 73 (Little and Brown, Boston, 1963).
Shibko, S., and Tappel, A. L., J. Cell. and Comp. Physiol., 61, 85 (1963).
Babson, A. L., Science, 123, 1082 (1956).
Cohen, S., and Gordon, A. H., Biochem. J., 70, 544 (1958).
Hsu, L., and Tappel, A. L., J. Cell. Biol., 23, 233 (1964).
Miller, G. L., Anal. Chem., 31, 964 (1959).
Friedberg, F., Tarver, H., and Greenberg, D., J. Biol. Chem., 173, 355 (1948).
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HSU, L., TAPPEL, A. Catheptic Activity of the Gastrointestinal Tract, Liver, Spleen and Kidney of the Rat. Nature 207, 1200 (1965). https://doi.org/10.1038/2071200a0
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DOI: https://doi.org/10.1038/2071200a0
