Abstract
Hayhoe and Quaglino1 have reported investigations of RNA metabolism in normal human leucocytes when cultured with phytohaemagglutinin, using uridine -5-3H as a specific precursor of RNA. They found little evidence of cytoplasmic labelling after terminal incubation for 1 h with tritiated uridine (0.5 μc./ml.), either at 24, 48 or 72 h of culture.
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References
Hayhoe, F. G. J., and Quaglino, D., Nature, 205, 151 (1965).
MacNeal, W. J., J. Amer. Med. Assoc., 78, 1122 (1922).
Yoffey, J. M., Winter, G. C. B., Osmond, D. G., and Meek, E. S., Brit. J. Haematol., 11, 488 (1965).
Harris, H., Nature, 201, 863 (1964).
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WINTER, G., YOFFEY, J. Cytoplasmic Labelling with Uridine-5-3H in Human Lymphocytes cultured with Phytohaemagglutinin. Nature 208, 1018–1019 (1965). https://doi.org/10.1038/2081018a0
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DOI: https://doi.org/10.1038/2081018a0