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Linkage in Man: the Inv and the Lp Serum Type Systems

Abstract

THE new serum type system Lp1 is a useful genetic marker system, the frequency of the Lpa gene being approximately 0.18 in Caucasians2,3 and test reagents unrestrictedly available. Concerning the serum type system Inv (refs. 4 and 5), test reagents have been relatively difficult to obtain, but are now increasingly available5–8. The established Inva or Inv1a gene frequencies, 0.06–0.10 in Caucasians and considerably higher in other populations, would indicate common use of this marker system in the future. This pre-supposes the elucidation of the genetics of this system, including analysis of linkage relationships. This communication provides data on the Inv–Lp linkage relation.

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References

  1. Berg, K., Acta Path. Microbiol. Scand., 59, 369 (1963).

    Article  CAS  Google Scholar 

  2. Mohr, J., and Berg, K., Acta Genet. (Basel), 13, 343 (1963).

    CAS  PubMed  Google Scholar 

  3. Berg, K., and Wendt, G. G., Humangenetik, 1, 24 (1964).

    CAS  PubMed  Google Scholar 

  4. Ropartz, C., Nature, 189, 586 (1961).

    Article  ADS  CAS  Google Scholar 

  5. Steinberg, A. G., in Progress in Medical Genetics, 2 (Grune and Stratton, London and New York, 1962).

    Google Scholar 

  6. Herzog, P., and Drdova, A., Vox Sang. (Basel), 6, 636 (1961).

    Article  CAS  Google Scholar 

  7. Ropartz, C., Rivat, L., and Rousseau, P.-Y., Ninth Congr. Int. Soc. Blood Transf., Mexico (1962).

  8. Ritter, H., and Schmidtmann, E., Humangenetik, 1, 144 (1964).

    CAS  PubMed  Google Scholar 

  9. Berg, K., Acta Path. Microbiol. Scand., 62, 276 (1964).

    Article  CAS  Google Scholar 

  10. Finney, D. J., Ann. Eugen. (Lond.), 10, 171 (1940).

    Article  Google Scholar 

  11. Smith, C. A. B., Amer. J. Hum. Genet., 11, 289 (1959).

    CAS  PubMed  Google Scholar 

  12. Berg, K., and Mohr, J., Acta Genet. (Basel), 13, 349 (1963).

    CAS  PubMed  Google Scholar 

  13. Steinberg, A. G., and Matsumoto, H., Hum. Biol., 36/2, 77 (1964).

    Google Scholar 

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GEDDE-DAHL, T., BERG, K. Linkage in Man: the Inv and the Lp Serum Type Systems. Nature 208, 1126 (1965). https://doi.org/10.1038/2081126a0

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