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Derivatives of 2-Aminoethyl-guanidine and of a Eugenol as Virus Inhibitors
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  • Letter
  • Published: 23 October 1965

Derivatives of 2-Aminoethyl-guanidine and of a Eugenol as Virus Inhibitors

  • SÁNDOR PÁCSA1,
  • OLGA H. HANKOVSZKY2 &
  • KÁLMÁN HIDEG2 

Nature volume 208, page 409 (1965)Cite this article

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Abstract

IT is a well-known fact that certain structurally different chemicals inhibit the synthesis of viral RNA1–3. In this communication a few substances which inhibit virus multiplication are described. These are the following: 2-(β-aminoethyl) pyridine (AEP), its substituted derivatives; the 2-pyridyl-ethyl-guanidine sulphate (Pyg)4, the 2 - (5 - allyl - 3 - methoxy - 2 - hydroxy - benzyl) - β - (α - pyridyl) ethyl amine (H-99)5 and ‘Ismelin’ 2-octahydro-1-azocynil ethyl guanidine sulphate4. Guanidine hydrochloride was used as control.

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References

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  5. Hankovszky, O., and Hideg, K. (unpublished results).

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  8. Maxwell, R. A., Plummer, A. J., Schneider, F., Povalski, H., and Daniels, A. J., J. Pharmacol. Exp. Therap., 128, 22 (1960).

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Author information

Authors and Affiliations

  1. Institute of Microbiology, Pécs

    SÁNDOR PÁCSA

  2. Institute of Pharmacology, Pécs, Hungary

    OLGA H. HANKOVSZKY & KÁLMÁN HIDEG

Authors
  1. SÁNDOR PÁCSA
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  2. OLGA H. HANKOVSZKY
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  3. KÁLMÁN HIDEG
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PÁCSA, S., HANKOVSZKY, O. & HIDEG, K. Derivatives of 2-Aminoethyl-guanidine and of a Eugenol as Virus Inhibitors. Nature 208, 409 (1965). https://doi.org/10.1038/208409a0

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  • Issue date: 23 October 1965

  • DOI: https://doi.org/10.1038/208409a0

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