Abstract
ELECTRON microscopic investigations of the carotid body1–6 have provided some basic information concerning the cell types present and the characteristics of nerve fibres and blood vessels. Since the early work of De Castro7,8, the glomus cells have been widely assumed to be the chemoreceptor component of the carotid body. Lever, Lewis and Boyd5 found that nerve fibres containing a concentration of mitochondria and microvesiclos terminated near glomus cells. Ross4, on the other hand, found that the few terminal axons in apposition with glomus cells did not contain mitochondria or synaptic vesicles. In neither investigation was specialization of opposing cell membranes observed. In the examination of the carotid body recorded here, further characteristics of both the nerve endings on the glomus cells and vascular endothelium have been determined.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Engström, H., Hamberger, C.-A., Holmer, M., and Rignell, N. S., Acta otolaryng., Stockh., 48, 379 (1957).
Garner, C. M., and Duncan, D., Anat. Rec., 130, 691 (1958).
Hoffman, H., and Birrell, J. H. W., Acta Anat., 32, 297 (1958).
Ross, L. L., J. Biophys. Biochem. Cytol., 6, 253 (1959).
Lever, J. D., Lewis, P. R., and Boyd, J. D., J. Anat. (Lond.), 93, 478 (1959).
De Kock, L. L., and Dunn, A. E. G., Nature, 202, 821 (1964).
De Castro, F., Trab. Lab. Invest. Biol. Univ. Madr., 24, 365 (1926).
De Castro, F., Trab. Lab. Invest. Biol. Univ. Madr., 25, 331 (1927).
De Kock, L. L., Acta Anat., 21, 101 (1954).
Gray, E. G., in Electron Microscopic Anatomy, edit. by Kurtz, S. M., 369 (Academic Press, New York, 1964).
Taxi, J., C.R. Acad. Sci., Paris, 252, 174 (1961).
Roth, T. F., and Porter, K. R., J. Cell. Biol., 20, 213 (1964).
Rosenbluth, J., and Wissig, S. L., J. Cell. Biol., 23, 307 (1964).
Stehbens, W. E., Nature, 207, 197 (1965).
Gray, E. G., in Electron Microscopy in Anatomy, edit. by Boyd, J. D., Johnson, F. R., and Lever, J. D., 54 (Arnold, London, 1961).
De Lorenzo, A. J., Bull. Johns Hopk., 108, 258 (1961).
Hamlyn, L. H., J. Anat. (Lond.), 96, 112 (1962).
Heymans, C., and Neil, E., Reflexogenic Areas of the Cardiovascular System, 190 (Churchill, London, 1958).
Anichkov, S. V., and Belen'kii, M. L., Pharmacology of the Carotid Body Chemoreceptors translation by Crawford, R., 147 (Pergamon, London, 1963).
Eyzaguirre, C., Koyano, H., and Taylor, J. R., J. Physiol. (Lond.), 178, 463 (1965).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
BISCOE, T., STEHBENS, W. Electron Microscopic Observations on the Carotid Body. Nature 208, 708–709 (1965). https://doi.org/10.1038/208708a0
Issue date:
DOI: https://doi.org/10.1038/208708a0
This article is cited by
-
New theory for receptor mechanism of carotid body chemoreceptors
Nature (1975)
-
Die Feinstruktur des Glomus caroticum beim Menschen
Zeitschrift f�r Zellforschung und Mikroskopische Anatomie (1970)
-
Untersuchungen �ber den Einflu� pulmonaler und cerebraler Atemst�rungen auf das Zellmuster der Carotisk�rperchen beim Menschen
Virchows Archiv A Pathologische Anatomie (1968)
-
Spontaneous Activity recorded from the Central Cut End of the Carotid Sinus Nerve of the Cat
Nature (1967)
-
Electron Microscopy of the Chemoreceptor Cells of the Carotid Labyrinth of the Toad
Nature (1966)